Entries by merlin_admin

Roberta Angioni, University of Padua presents MERLIN at the Pediatric Research Institute meeting

Roberta Angioni of the Department of Biomedical Science at the University of Padua presented MERLIN’s objectives and results during  an invited talk entitled “Mesenchymal stem cells and their extracellular vesicles in the control of pathological angiogenesis” at the Pediatric Research Institute (IRP) meeting held April 7, 2018, at the Villa Pace Park Hotel, Preganziol in Treviso, Italy. Roberta […]

Merlin Newsletter Winter 2017 – 2018

The Merlin Newsletter for Winter 2017 – 2018 has just been issued! This is the second edition of our newsletter and includes the following sections: Refresher Course – a reminder of the project’s key aims and objectives Forging Ahead – a brief update on recent progress Read All About it – details of some of […]

Merlin team meet in Padua

The Merlin partners met in Padua on 22 and 23 January for our most recent plenary. The team heard updates from workstreams across the project and discussed the reports to be submitted to the EU by the end of January. MSC manufacture and plans for the clinical trial were also a key focus. An exploitation […]

S. de Witte, Erasmus MC presents MERLIN findings in 2017

S. de Witte of Erasmus University Medical Center in Rotterdam took to the road in 2017 to present MERLIN results at five conferences in Belgium, The Netherlands and Spain: · Erasmus MC, Science days of the Department of Internal Medicine, Antwerp Poster: IMPACT OF CULTURE EXPANSION AND INFLAMMATORY CYTOKINE CHALLENGE ON DNA METHYLATION PROFILES IN MSC […]

MERLIN will present at EU-MSC2 meeting in Leiden in September

Hosted by Leiden University Medical Center, the EU MSC2 2017 meeting in Leiden, NL on September 12th and 13th will assemble twelve EU-funded, mesenchymal stromal cell-focussed consortia. Projects to be presented include: REDDSTAR, REACH, RETHRIM, Stellar, MERLIN, Nephstrom, SCIENCE, VISICORT and Adipoa-2, AUTOSTEM, BOOSTB4, SEPCELL, RESSTORE, and RESPINE. This two day, interactive meeting will be held at the Stadsgehoorzaal Leiden. Three overarching aspects of the EU-MSC2 meeting include: mechanisms of action and […]

Proteomic analysis of the secretome of human bone marrow-derived MSCs

MERLIN team at the Universitá degli Studi di Padova publish “Proteomic analysis of the secretome of human bone marrow-derived mesenchymal stem cells primed by pro-inflammatory cytokines” in the Journal of Proteomics, 21July 2017 Congratulations to all authors: Elisa Maffioli, Simona Nonnis, Roberta Angioni, Fabiana Santagata, Bianca Calí, Lucia Zanotti, Armando Negri, Antonella Viola, Gabriella Tedeschi. In […]

Merlin Article Published on Optimisation of MSC

A new Merlin article on Optimisation of MSC has just been published in Stem Cell Research and Therapy. The piece is entitled “Cytokine treatment optimises the immunotherapeutic effects of umbilical cord-derived MSC for treatment of inflammatory liver disease” and was lead by Samantha de Witte from Erasmus MC in the Netherlands. The paper is open […]

Merlin Meet in Rotterdam

The Merlin team had a very successful plenary in Rotterdam on 10 and 11 May. Updates were presented on each WP. MSC production and preparation for the upcoming trial were naturally a key focus at this stage of the project. Publications and plans for future work were also discussed. Many thanks to EMC for hosting […]

MERLIN article for publication in Cytotherapy

A Merlin paper on the impact of long-term in vitro expansion on MSCs has been accepted for publication in Cytotherapy. The article is entitled “Aging of bone marrow and umbilical cord–derived mesenchymal stromal cells during expansion” (by Samantha de Witte (pictured above), Eleonora E. Lambert, Ana Merino, Tanja Strini, Hannie J.C.W. Douben, Lisa O’Flynn, Steve […]