The University of Birmingham has launched a trial which could lead to a ground-breaking new way of treating people with two types of chronic liver disease. Up to 56 patients are being recruited to take part in the MERLIN trial, which will investigate the safety and efficacy of a new cellular immunotherapy in patients with […]
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Would you like to read a capsule summary of what the MERLIN project has accomplished? Well, please download and share the MERLIN Final Flyer here.
On Tuesday, November 20, 2018, Dr Samantha de Witte successfully defended her PhD. research at Erasmus Medical Center, Rotterdam, NL. The title of Dr de Witte’s dissertation was “Probing the immunomodulatory potential of mesenchymal stromal cells”. MERLIN Coordinator Prof Phil Newsome, University of Birmingham, UK was one of Samantha’s external examiners. Congratulations, Samantha!
MERLIN PhD student Roberta Angioni of the Università degli Studi di Padova was selected for a “Bright Spark” presentation during the 5th European Congress of Immunology (ECI). The ECI meeting was held in Amsterdam on September 2-5, 2018. Roberta remarks: “With my great pleasure, I was awarded with the “EFIS-Biolegend Bright Sparks Award for a presentation judged […]
Erasmus Medical Center PhD student Jesus Sierra presented Merlin data at the Congress of the Transplantation Society in Madrid in July 2018. The title of Jesus’ talk was: Monocytic cells phagocytose therapeutic mesenchymal stem cells, which induces polarization, relocation and immune regulation. Jesus Sierra in conjunction with Martin Hoogdujin, his mentor claimed the mentor-mentee award at […]
The MERLIN study “Epigenetic changes in umbilical cord mesenchymal stromal cells upon stimulation and culture expansion” has been recently published in Cytotherapy The Journal of Cell Therapy. The body of research by Samantha F.H. de Witte1, Fleur S. Peters1, Ana Merino1, Sander S. Korevaar1, Joyce B.J. van Meurs2, Lisa O’Flynn3, Steve J. Elliman3, Philip N. Newsome4–6, […]
Head of Process Development at Orbsen Therapeutics, Limited, Dr Lisa O’ Flynn attended the 3rd Annual Bioprocessing and Advanced Cellular Therapies Congress in Frankfurt, Germany. The meeting was held on the 29th-30th of May 2018. Lisa gave an oral presentation entitled ” CD362 to ORBCEL: the rapid development of a novel stromal cell therapy ” wherein […]
Roberta Angioni of the Department of Biomedical Science at the University of Padua presented MERLIN’s objectives and results during an invited talk entitled “Mesenchymal stem cells and their extracellular vesicles in the control of pathological angiogenesis” at the Pediatric Research Institute (IRP) meeting held April 7, 2018, at the Villa Pace Park Hotel, Preganziol in Treviso, Italy. Roberta […]
A new MERLIN publication led by our team at Erasmus MC in Rotterdam, NL appeared in the journal Stem Cells on 17 January 2018. Authors of this paper are: Samantha F H de Witte , Franka Luk, Jesus M Sierra Parraga, Madhu Gargesha, Ana Merino, Sander S Korevaar, Anusha S Shankar, Lisa O’Flynn, Steve J Elliman, […]
The Merlin Newsletter for Winter 2017 – 2018 has just been issued! This is the second edition of our newsletter and includes the following sections: Refresher Course – a reminder of the project’s key aims and objectives Forging Ahead – a brief update on recent progress Read All About it – details of some of […]
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This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 602363. The material presented and views expressed here are the responsibility of the author(s) only. The EU Commission takes no responsibility for any use made of the information set out.